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<p><b>OBJECTIVE</b>To observe the clinical effect of acupuncture at Baihui(GV 20) and Shenting(GV 24) combined with rehabilitation for post-stroke cognitive impairment(PSCI).</p><p><b>METHODS</b>Fifty patients with PSCI were randomly assigned to an observation group and a control group,25 cases in each one. In the control group,basic treatment and regular rehabilitation were applied. In the observation group,acupuncture at Baihui(GV 20) and Shenting(GV 24) and the same therapies as the control group were used for continuous four weeks,once a day and five times a week. Mini-mental state examination(MMSE) and Montreal cognitive assessment(MoCA) were observed before and after treatment in the two groups.</p><p><b>RESULTS</b>After treatment,the scores of MMSE and MoCA were improved apparently(both<0.05),with better results in the observation group(both<0.05).</p><p><b>CONCLUSIONS</b>Acupuncture at Baihui(GV 20) and Shenting(GV 24) combined with basic treatment and regular rehabilitation can obviously improve the cognitive function of PSCI,and the effect is superior to that of basic treatment and regular rehabilitation.</p>
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Objective To observe the therapeutic effect of consciousness-restoring needling combined with comprehensive rehabilitation training on motor function and the activities of daily living of poststroke patients with hemiplegia. Methods Sixty qualified patients were evenly randomized into observation group and control group. All of the patients were given conventional medicine treatment and conventional rehabilitation training, and the treatment group was given consciousness-restoring needling additionally. The therapeutic effects were compared at the end of first session of treatment for 4 weeks and 12 weeks after the first session of treatment. The Fugl-Meyer motor assessment scale (FMA), modified Barthel Index (MBI) and Stroke-Specific Quality of Life Scale ( SS-QQL) were taken as the main evaluation indexes. Results The differences of FMA, MBI and SS-QOL scores were insignificant between the two groups before treatment ( P>0.05). At the end of treatment for 4 weeks, FMA, MBI and SS-QOL scores were increased in the two groups (P<0.05), and the increase was more obvious in the observation group (P<0.05). The results of follow-up till the 12th week showed that FMA, MBI and SS-QOL scores were still higher than the baseline level ( P<0.05). Conclusion Consciousness-restoring needling combined with comprehensive rehabilitation training has better effect on improving motor function and the activities of daily living of poststroke hemiplegia patients than comprehensive rehabilitation training alone.
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Objective To study the clinical effect of qi supplementation combined with rehabilitation on the severity of fatigue after ischcmic stroke in patients with qi deficiency. Methods Ninety ischemic stroke patients with qi deficiency were randomly divided into 3 groups of 30. The treatment group was treated with an oral decoction of qi-supplementing Chinese medicine and also rehabilitation. The Western medicine control group was treated with a Chinese medicine placebo, Western medicine and rehabilitation. The blank control group was treated with the Chinese medicine placebo and rehabilitation. All groups were evaluated using a stroke-specific quality of life scale ( SSQOL) and a fatigue severity scale (FSS) before and 4 weeks after treatment. Results After treatment, the average SS-QOL and FSS scores had improved significantly compared with those before treatment, especially in the two treatment groups. There was a significant difference between the treatment group and the Western medicine control group,and between the treatment group and the blank control group on both scales. There was also a significant difference between the Western medicine control group and the blank control group in terms of SS-QOL scores, but not FSSscores. Conclusion All 3 treatments alleviated fatigue in ischemic stroke patients with a qi deficiency. Qi supplementation combined with rehabilitation was the most effective, followed by Western medicine combined with rehabilitation.
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Objective To observe the effect of Tangbi Capsules(TC)on ultrastructure of sciatic nerve in diabetic rats.Methods SD diabetic rat models were induced by one-dose intraperitoneal injection of streptozotocin(50 mg/kg).Then the diabetic rats were randomized into 5 groups: model group,high-and low-dose TC groups(in the dose of 1 and 0.5 g?kg-1?d-1 respectively),mecobalamin(250 ?g?kg-1?d-1)group,and the combination group(receiving TC 0.5 g?kg-1?d-1 and mecobalamin 250 ?g?kg-1?d-1).Meanwhile,the normal control group was also set up.After treatment for 4 weeks,the changes of utrastructure of sciatic nerve in different groups were observed under electron microscope.Results The pathological changes of sciatic nerve in diabetic rats were similar with the clinical peripheral neuropathy.The protective effect on sciatic nerve in high-dose TC group was superior to that in low-dose TC group and mecobalamin group,and the combination group had the best protective effect.Conclusion TC exerts certain protective effect on diabetic peripheral neuropathy.
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Objective To assess the cognitive function of subjects with brain injury with Loewenstein occupational therapy cognitive assessment (LOTCA) and mini-mental status examination (MMSE). Methods Two groups of subjects participated in this study. One group consisted of 36 subjects with brain injury (patient group). They were 28 males and 8 females,aged 61.0?16.7 years old. The other group was made of 44 healthy subjects (control group),with 25 males and 19 females,aged 55.4?23.7 years old. All subjects were assessed using LOTCA and MMSE and the results of them were analyzed. Results There was high correlation between the total scores of LOTCA and those of MMSE ( r =0.892,P
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Objective To study the validity and reliability of the simplified Chinese version of Loewenstein Occupational Therapy Cognitive Assessment (LOTCA). MethodsThe English version of LOTCA was translated into the simplified Chinese first and then translated back to English to ensure its reliability in Chinese version.The we recruited two groups of volunteers to participate in the study. One group consisted of 36 patients with brain disorders (patient group), The other group consisted of 43 subjects without neurological disorders (control group). All the subjects were assessed with LOTCA and Mini-Mental State Examination (MMSE) within one session and on different days, respectively by two independent raters. Scores of LOTCA and MMSE were analyzed with Spearman correlation coefficient to test the validity of LOTCA. Intra-class coefficients (ICCs) were used to examine the intra-rater and inter-rater reliability of LOTCA. And Mann-Whitney test of non-parameters analysis was used to detect the sensitivity of LOTCA. ResultsThere was high correlation between the scores of LOTCA and that of MMSE ( r =0.9852- 0.9939 ). ICCs of LOTCA were 0.9923( P
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Objective To investigate the therapeutic effects of one session of transcutaneous electrical nerve stimulation (TENS) on regional cerebral blood flow (rCBF) in stroke patients. Methods Twenty-two stroke patients were randomly divided into a treatment group and a control group. The rCBF changes in all patients were examined using single positron emission computerized tomorgraphy (SPECT). Scans were performed twice with an interval of 1 h. The patients in the treatment group were treated with TENS during the 1h interval. Eight acupuncture points on the paralyzed limb (LI15, LI11 , LI4, SJ5 on the upper limb and ST36, ST41 , GB34, BL60 on the lower limb) were treated. rCBF changes in the affected hemisphere, as well as at mirror sites on the affected hemisphere, were analyzed in terms of their semi-quantity value, asymmetry index and the percentage change over the two sessions. Results The radioactivity counts, semi-quantity values and percentage changes were significantly greater in the TENS group, while the asymmetry index was significantly lower than that in the control group. Conclusion TENS can increase rCBF in both the affected and unaffected hemispheres of stroke patients. That TENS improves motor function after stroke may be related to increasing the rCBF levels and stimulating functional activity in the brain cells.
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Objective To observe the therapeutic effects of electrical stimulation of pelvic floor muscles on urinary incontinence (UI) in patients with incomplete spinal cord injury (ISCI). Methods Seven patients (5 males and 2 females; average age: 32.5 years; average duration after injury: 7.5 months) with ISCI were treated with ESPFM applied on rectum (for male) or vagina (for female) for 30～45 min,once a day, 5 days a week for (2～3) months. The rate of success on stopping using catheters and the frequency and amount of urination were observed during treatment. Results Catheters were taken out successfully from all patients 2～3 weeks after treatment. Five out of the 7 patients had more self-control of urination than incontinence after 8 weeks of treatment though there was no significant difference in the amount of the urination. Conclusion ESPFM might improve the function of urinary bladder in patients with incomplete spinal cord injury.